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Inbred Strains of Mice: NON


Inbr (Komeda) 27. Albino: c. Origin: A non-diabetic substrain with the same origin as NOD. Has a unique MHC class II haplotype (Acha-Orbea and Scarpellino 1991). Anti-BPO IgE monoclonal antibody failed to produce potent systemic sensitization sufficient for provocation of lethal shock in most aged (6 to 10 months) mice (c.f. 5/8) (Harada et al 1991). Maint. by Wak.

Acha-Orbea H. and Scarpellino L. (1991) Nonobese diabetic and nonobese nondiabetic mice have unique MHC class II haplotypes. Immunogenet. 34, 57-59.

Harada M., Nagata M., Takeuchi M., Ohara T., Makino S., and Watanabe A. (1991) Age-dependent difference in susceptibility to IgE antibody- and IgG1 antibody-mediated passive anaphylactic shock in the mouse. Immunological Investigations 20, 515-523.

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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