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Inbred Strains of Mice: JU


Inbr: F41+60 (Ct). Albino. Genet: a, c. Origin: Falconer 1952, from crosses involving Goodale's and MacArthur's large strains, Bateman's high-lactation strain and various mutant stocks with about 50% of C57BL/Fa ancestry. It was the only survivor from an inbreeding experiment involving twenty lines (Falconer, 1960b). Falconer to Cattanach in 1966.


Average first litters 9; high prenatal mortality (50%) in second litters when gestation is concurrent with suckling first litter; low penetrance of nil. (Staats, 1976). Lm maintains a number of substrains with different pigment mutations including a non-albino +c . Maint. by Ct.


Inbr. N5F59 (Ct). Black, a,C. Derived from a cross between JU female (F41) with a CBA male, five backcrosses to JU, then selection for the CC genotype upon sib mating.


Inbr. N5F59. Agouti, +. Origin: same as JU/Ct-C, but selection for the agouti phenotype upon sib mating. Charac. Background enhances expression of Sl and Wv with regard to coat colour.

Staats J. (1976) Standardized nomenclature for inbred strains of mice: Sixth listing. Cancer Res. 36, 4333-4377. \par

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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