Inbred Strains
of Mice: CPB
Inbr: 42. Genet:
b,
d. Origin: At Centraal Proefdierenbedrijf
TNO, Holland (Cpb), about 1950.
Characteristics
Females often have a pair of non-lactating supernumerary nipples (
Staats,
1976).
CPB-K
Inbr: 54. Genet:
a, B, c, d, P. Origin: As CPB-H. Former designation
KC discontinued.
Characteristics
Excitable; small litters; amylase type B (other CPB strains are type A).
CPB-MO
Inbr: 37. Genet:
c. Origin: Institute of Tropical Hygiene, Amsterdam,
to Cpb 1957.
Characteristics
100% brachypodism due to a recessive gene.
CPB-N
Inbr: 47. Genet:
a,
b, p. Origin: As CPB-H.
Characteristics
Normal sex difference in major urinary protein content of serum and in
reaction to hexobarbital.
CPB-P
Inbr: 39. Genet:
a, b, d, p.
Characteristics
Reacts to LSD with head twitching. Very light red-eyed grey.
CPB-Q
Inbr (Cpb): ? + 61. Genet:
a, B, ce, D,
P. Origin: Hagedoorn, Holland, to Hirschfeld 1937, to Cpb 1949.
Characteristics
More susceptible to tuberculosis than most strains; reacts to LSD with
head twitching.
CPB-R
Inbr: ?+50. Genet:
a, b, c, D, P. Origin: `Rhodesfarm', South
Africa, to Compton, England, to Hagedoorn, Holland, to Cpb 1949.
CPB-S
Inbr: ? + 59. Genet:
A, B, c, D, P. Origin: Rockefeller Institute,
probably same origin as BSVS, BRVR, etc., to Laidlaw (Hampstead), to Hagedoorn,
to Cpb 1949.
Characteristics
Rather aggressive, especially males (Cpb), territorial, with a sensitive
aggression-flight balance; adapted to surface-living rather than hole-living.
CPB-TK
Inbr: 37. Genet:
a, b, d, s, W. Origin: Cross between CPB-T and
CPB-K in 1953.
Characteristics
Macrocytic anaemia.
CPB-V
Inbr: 54. Genet:
cch . Origin:
Hagedoorn, to Cpb 1949.
Characteristics
Males have low major urinary protein in serum; no sex difference in response
to hexobarbital.
CPB-WG
Inbr: 33. Genet:
a. Origin: Waltzing mice from Hagedoorn in 1949.
Crossed with strain G, now extinct, in 1953.
Characteristics
Carries a waltzer-shaker-like mutant; expression varies from fairly normal
walking to circling; very excitable; not deaf.
CPB-WV
Inbr: 39. Genet:
Wv/w, A. Origin:
Gruneberg, to Cpb in 1956.
Characteristics
Macrocytic anaemia.
Staats J. (1976) Standardized
nomenclature for inbred strains of mice: Sixth listing. Cancer Res.
36, 4333-4377.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW
Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,
UK
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