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Inbred Strains of Mice: CL


Inbr: F20 +. Strain developed by Fraser from a heterogeneous stock carrying the msl gene (migratory spot lesion a variable white spot on the retina), crossed to A/J and subsequently inbred with selection for high frequency of spontaneous cleft lip. Frequency of the latter now 26% in viable 17-day embryos (Bornstein et al., 1970., 1970).

Bornstein S., Trasler D. G., and Fraser F. C. (1970) Effect of the uterine environment on the frequency of spontaneous cleft lip in CL/Fr mice. Teratology 3, 295-298. \par

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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