of Mice: C3HA
Inbr (Y) 102. Agouti:+
Pogosianz, C3H female
x A male, followed by sib mating.
Originally 30% mammary tumours, but has declined. Susceptible to hepatic
carcinogens. Treatment with 1,2-dimethylhydrazine resulted in 59% of mice
developing hemorrhagic ovatian lesions but no unterine sarcome. The latter
could be induced by DMH and estradiol dipropionate (Tutusov et al, 1994).
Clonidene failed to produce an aggressive behavioural response (cf 3/9)
(Nikulina and Klimek, 1993).
Maint. by Y.
E. M. and Klimek V. (1993) Strain differences in clonidine-induced aggressiveness
in mice and its interaction with the dopamine system. Pharmacol. Biochem.
Behav. 44, 821-825.
INBRED STRAINS OF MICE
Updated 9 Apr. 1998
MRC Toxicology Unit, Hodgkin Building,
University of Leicester,