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Inbred Strains of Mice: BXD


Inbr 30+. Set of 24 recombinant inbred strains developed by B.A.Taylor from C57BL/6J x DBA/2J. BXD-31 has low osmotic fragility of erythrocytes due to variation at a single genetic locus causing up-regulation of K-Cl cotransport which induces cell dehydration, a K+ deficit and resistance to osmotic lysis (Armsby et al, 1996). Maint. by Ty.

Armsby C. C., Stuarttilley A. K., Alper S. L., and Brugnara C. (1996) Resistance to osmotic lysis in BXD-31 mouse erythrocytes -association with up-regulated K-Cl cotransport. American Journal of Physiology-Cell Physiology 39, C866-C877. \par

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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