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Inbred Strains of Mice: BPL

BPL /1

Inbr (J, 1998) F55. White bellied agouti. Origin: Gunther Schlager, U. of Kansas. Genetic selection for low blood pressure initiated in 1966 from a base population derived from an 8-way cross among LP/J, SJL/J, BALB/cJ, C57BL/J, 129/J, CBA/J, RF/J and BDP/J. Inbreeding avoided until F23 when several inbred substrains were initiated. Strain has low systolic blood pressure, long life span (approx. 50% longer than BPH/2) and high norephinephrine content in whole brain (Schlager 1994) (see also BPH). Maintained by J.


Schlager G. (1994) Genetic hypertension in the mouse, in Handbook of Hypertension Vol. 16 Experimental and Genetic Models of Hypertension (Ganten D. and de Jong W., eds), pp. 158-172. Elsevier, Amsterdam, New York, Oxford. \par


INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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last database update
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