About   Help   FAQ
Inbred Strains of Mice: BL

BL

Inbr: F108. Albino. Genet: a, b, c strain developed by Lynch from Bagg albino stock via Strong, and maintained at Rockefeller Institute since 1921.


Characteristics

Low mammary tumours, some lung tumours in older mice (Staats, 1976). Ovaries often appear pale and enlarged and have an infiltration of amyloid. Thought to be due to necrotising arteritis in which there is a thickening of the walls of the vessels to duodenum and ovaries due to a deposition of eosinophilic material within the intima and media (Deringer, 1959b). Aseptic necrosis of bone in 22% of females often resulting in fracture of femoral neck and other complications, so that the animals are severely crippled (Sokoloff and Haberman, 1958).


Deringer M. K. (1959b) Occurrence of tumors, particularly mammary tumors in agent-free strain C3HeB mice. J. Natl. Cancer Inst. 22, 995-1002. \par

Sokoloff L. and Haberman R. T. (1958) Idiopathic necrosis of bone in small animals. Arch. Pathol. 65, 323-330. \par

Staats J. (1976) Standardized nomenclature for inbred strains of mice: Sixth listing. Cancer Res. 36, 4333-4377. \par


INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/20/2017
MGI 6.10
The Jackson Laboratory