AE

Inbr (Nctr) 80. Pink-eyed fawn: a^e,b,d,p,se. Origin: Two litters of stock 3H-220 from Hollander, Iowa to Inst. Cancer Research, PA in 1962 at about F3. To Nctr in 1972. Caesarian-derived and fostered to C3Hf in 1980. Markedly lower electroconvulsive thresholds without increased susceptibility to seizures induced by pentylenetetrazol. Low responsiveness to phenobarbital and valproic acid. Possibly useful for epilepsy research (Loscher et al 1986) Maint. by Nctr

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Loscher W., Czuczwar S. J., and Wolff G. L. (1986) AE mice-an inbred mouse strain with interesting features for epilepsy research. Epilepsia 27, 657-664.

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INBRED STRAINS OF MICE
Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK