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Inbred Strains of Mice: AB


Inbr: 40 +. Genet: c. Origin: Agnes Bluhm to Hertwig in 1934, to Fortner in 1945, to Röhrer in 1949, to Jena in 1952. b x s inbreeding started 1959.


35-54% leukaemia and reticulosarcomatosis in virgin females; 15-30% flbro-sarcoma in virgins; moderate incidence of primary lung tumours in both sexes; sensitive to casein-induced amyloidosis (Staats, 1976); good vitality and fertility (Hg). High incidence of spontaneous amyloidosis (Zschiesche, 1972).

Staats J. (1976) Standardized nomenclature for inbred strains of mice: Sixth listing. Cancer Res. 36, 4333-4377.

Zschiesche W. (1972) Spontaneous amyloidosis of the mouse. Acta Pathol. Microbiol. Scand. A 80 Suppl. 233, 135-140.

Updated 9 Apr. 1998
Michael FW Festing
MRC Toxicology Unit, Hodgkin Building,
University of Leicester, UK

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