Phenotype Images associated with this Gene

Symbol
Name
ID

Rpe65
retinal pigment epithelium 65
MGI:98001

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Click on allele symbol for full phenotype details.

Caption: Effect of genetic depletion of 11-cis-retinal production (Lrat^tm1Kpal/Lrat^tm1Kpal) on retinal degeneration in Rho^tm1.1Kpal/Rho⁺ mice (details)

Represented Alleles:

Lrat^tm1Kpal, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); targeted mutation 1, Krzysztof Palczewski

Rho^tm1.1Kpal, rhodopsin; targeted mutation 1.1, Krzysztof Palczewski

Rpe65^450L, retinal pigment epithelium 65; 450 Leucine

Rpe65^450M, retinal pigment epithelium 65; 450 Methionine

Copyright: This image is from Sakami S, J Biol Chem 2011 Mar 25;286(12):10551-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:170648

Caption: Photoreceptor degeneration without exposure to bright light in Rpe65^rd12/Rpe65^rd12 Rho^Tvrm4/Rho⁺ mice (details)

Represented Alleles:

Rho^Tvrm4, rhodopsin; translational research vision model 4

Rpe65^rd12, retinal pigment epithelium 65; retinal degeneration 12

Copyright: This image is from Budzynski E, J Biol Chem 2010 May 7;285(19):14521-33 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:159523

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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