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Phenotype Images associated with this Gene
Symbol
Name
ID
Pthlh
parathyroid hormone-like peptide
MGI:97800


9 phenotype image(s) for Pthlh alleles
Showing image(s) 1 to 9

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Click on allele symbol for full phenotype details.

Caption: Pthlhtm2Ack/Pthlhtm2Ack mice show growth retardation, premature aging, osteopenia, kyphosis, muscle atrophy, decrease in adipose tissue, swelling of the brain, and thin skin (details)
Represented Alleles:
Pthlhtm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis
Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
Caption: Skeletal growth retardation caused by impaired growth plate chondrocyte proliferation in Pthlhtm2Ack/Pthlhtm2Ack mice (details)
Represented Alleles:
Pthlhtm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis
Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
Caption: Pthlhtm2Ack/Pthlhtm2Ack mice develop severe premature osteoporosis resulting from defects of osteoblastic bone formation (details)
Represented Alleles:
Pthlhtm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis
Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
Caption: Alizarin red S stained skeletal images of hemizygous and homozygous Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk/Pthlhtm1Hmk mice (details)
Represented Alleles:
Pthlhtm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHR1*H223R)AHju, transgene insertion A, Harald Juppner
Copyright: This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
Caption: Histological tibiae sections of mice homozygous for Tg(Col2a1-PTHR1*H223R)AHju, mice homozygous for Tg(Col2a1-PTHR1*H223R)AHju and Pthlhtm1Hmk and mice homozygous for Pthlhtm1Hmk (details)
Represented Alleles:
Pthlhtm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHR1*H223R)AHju, transgene insertion A, Harald Juppner
Copyright: This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
Caption: Skeletal phenotypes and tibial histology of Pthtm1Dgo/Pthtm1Dgo, Pthlhtm1Hmk/Pthlhtm1Hmk and Pthtm1Dgo/Pthtm1Dgo Pthlhtm1Hmk/Pthlhtm1Hmk mice (details)
Represented Alleles:
Pthtm1Dgo, parathyroid hormone; targeted mutation 1, David Goltzman
Pthlhtm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Copyright: This image is from Miao D, J Clin Invest 2002 May;109(9):1173-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76407
Caption: Quantitation of bone parameters of Pthtm1Dgo/Pthtm1Dgo, Pthlhtm1Hmk/Pthlhtm1Hmk and Pthtm1Dgo/Pthtm1Dgo Pthlhtm1Hmk/Pthlhtm1Hmk mice (details)
Represented Alleles:
Pthtm1Dgo, parathyroid hormone; targeted mutation 1, David Goltzman
Pthlhtm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Copyright: This image is from Miao D, J Clin Invest 2002 May;109(9):1173-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76407
Caption: Skeletal phenotypes of wild type, Tg(Col2a1-PTHLH)2Ecw/0, Pthlhtm1Hmk/Pthlhtm1Hmk, and Pthlhtm1Hmk/Pthlhtm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 mice (details)
Represented Alleles:
Pthlhtm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHLH)2Ecw, transgene insertion 2, Eleanor C Weir
Copyright: This image is from Philbrick WM, Proc Natl Acad Sci U S A 1998 Sep 29;95(20):11846-51. Copyright 1998 National Academy of Sciences, U.S.A. J:50144
Caption: Dental phenotype of Pthlhtm1Hmk/Pthlhtm1Hmk mice rescued with Tg(Col2a1-PTHLH)2Ecw and Tg(PTHLH)7Wmp transgenes (details)
Represented Alleles:
Pthlhtm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg
Tg(Col2a1-PTHLH)2Ecw, transgene insertion 2, Eleanor C Weir
Tg(PTHLH)7Wmp, transgene insertion 7, William M Philbrick
Copyright: This image is from Philbrick WM, Proc Natl Acad Sci U S A 1998 Sep 29;95(20):11846-51. Copyright 1998 National Academy of Sciences, U.S.A. J:50144

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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory