Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Pthlh
parathyroid hormone-like peptide
MGI:97800

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Click on allele symbol for full phenotype details.

	Caption: Pthlh^tm2Ack/Pthlh^tm2Ack mice show growth retardation, premature aging, osteopenia, kyphosis, muscle atrophy, decrease in adipose tissue, swelling of the brain, and thin skin (details) Represented Alleles: Pthlh^tm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
	Caption: Skeletal growth retardation caused by impaired growth plate chondrocyte proliferation in Pthlh^tm2Ack/Pthlh^tm2Ack mice (details) Represented Alleles: Pthlh^tm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
	Caption: Pthlh^tm2Ack/Pthlh^tm2Ack mice develop severe premature osteoporosis resulting from defects of osteoblastic bone formation (details) Represented Alleles: Pthlh^tm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
	Caption: Alizarin red S stained skeletal images of hemizygous and homozygous Tg(Col2a1-PTHR1H223R)AHju and Pthlh^tm1Hmk/Pthlh^tm1Hmk mice (details) Represented Alleles:* Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Histological tibiae sections of mice homozygous for Tg(Col2a1-PTHR1H223R)AHju, mice homozygous for Tg(Col2a1-PTHR1H223R)AHju and Pthlh^tm1Hmk and mice homozygous for Pthlh^tm1Hmk (details) Represented Alleles: Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Skeletal phenotypes and tibial histology of Pth^tm1Dgo/Pth^tm1Dgo, Pthlh^tm1Hmk/Pthlh^tm1Hmk and Pth^tm1Dgo/Pth^tm1Dgo Pthlh^tm1Hmk/Pthlh^tm1Hmk mice (details) Represented Alleles: Pth^tm1Dgo, parathyroid hormone; targeted mutation 1, David Goltzman Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Copyright: This image is from Miao D, J Clin Invest 2002 May;109(9):1173-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76407
	Caption: Quantitation of bone parameters of Pth^tm1Dgo/Pth^tm1Dgo, Pthlh^tm1Hmk/Pthlh^tm1Hmk and Pth^tm1Dgo/Pth^tm1Dgo Pthlh^tm1Hmk/Pthlh^tm1Hmk mice (details) Represented Alleles: Pth^tm1Dgo, parathyroid hormone; targeted mutation 1, David Goltzman Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Copyright: This image is from Miao D, J Clin Invest 2002 May;109(9):1173-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:76407
	Caption: Skeletal phenotypes of wild type, Tg(Col2a1-PTHLH)2Ecw/0, Pthlh^tm1Hmk/Pthlh^tm1Hmk, and Pthlh^tm1Hmk/Pthlh^tm1Hmk Tg(Col2a1-PTHLH)2Ecw/0 mice (details) Represented Alleles: Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Tg(Col2a1-PTHLH)2Ecw, transgene insertion 2, Eleanor C Weir Copyright: This image is from Philbrick WM, Proc Natl Acad Sci U S A 1998 Sep 29;95(20):11846-51. Copyright 1998 National Academy of Sciences, U.S.A. J:50144
	Caption: Dental phenotype of Pthlh^tm1Hmk/Pthlh^tm1Hmk mice rescued with Tg(Col2a1-PTHLH)2Ecw and Tg(PTHLH)7Wmp transgenes (details) Represented Alleles: Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Tg(Col2a1-PTHLH)2Ecw, transgene insertion 2, Eleanor C Weir Tg(PTHLH)7Wmp, transgene insertion 7, William M Philbrick Copyright: This image is from Philbrick WM, Proc Natl Acad Sci U S A 1998 Sep 29;95(20):11846-51. Copyright 1998 National Academy of Sciences, U.S.A. J:50144

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