Phenotype Images associated with this Gene

About Help FAQ

Support MGI: answer a 5-question survey

Phenotype Images associated with this Gene

Symbol
Name
ID

Pthlh
parathyroid hormone-like peptide
MGI:97800

Click on thumbnail to view full size image with links to phenotype annotations.
Click on allele symbol for full phenotype details.

	Caption: Pthlh^tm2Ack/Pthlh^tm2Ack mice show growth retardation, premature aging, osteopenia, kyphosis, muscle atrophy, decrease in adipose tissue, swelling of the brain, and thin skin (details) Represented Alleles: Pthlh^tm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
	Caption: Skeletal growth retardation caused by impaired growth plate chondrocyte proliferation in Pthlh^tm2Ack/Pthlh^tm2Ack mice (details) Represented Alleles: Pthlh^tm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
	Caption: Pthlh^tm2Ack/Pthlh^tm2Ack mice develop severe premature osteoporosis resulting from defects of osteoblastic bone formation (details) Represented Alleles: Pthlh^tm2Ack, parathyroid hormone-like peptide; targeted mutation 2, Andrew C Karaplis Copyright: This image is from Miao D, Proc Natl Acad Sci U S A 2008 Dec 23;105(51):20309-14. Copyright 2008 National Academy of Sciences, U.S.A. J:142669
	Caption: Skeletal images of wild-type and Tg(Col2a1-PTHR1H223R)AHju/Tg(Col2a1-PTHR1H223R)AHju mice (details) Represented Alleles: Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Histological sternum sections of wild-type, and mice hemizygous and homozygous for Tg(Col2a1-PTHR1H223R)AHju (details) Represented Alleles:* Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Light microscopy of tibiae from wild-type, hemizygous and homozygous Tg(Col2a1-PTHR1H223R)AHju, and homozygous Tg(Col2a1-PTHR1H223R)BHju mice. (details) Represented Alleles: Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Tg(Col2a1-PTHR1H223R)BHju, transgene insertion B, Harald Juppner Copyright: This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Alizarin red S stained skeletal images of hemizygous and homozygous Tg(Col2a1-PTHR1H223R)AHju and Pthlh^tm1Hmk/Pthlh^tm1Hmk mice (details) Represented Alleles:* Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Histological tibiae sections of mice homozygous for Tg(Col2a1-PTHR1H223R)AHju, mice homozygous for Tg(Col2a1-PTHR1H223R)AHju and Pthlh^tm1Hmk and mice homozygous for Pthlh^tm1Hmk (details) Represented Alleles: Pthlh^tm1Hmk, parathyroid hormone-like peptide; targeted mutation 1, Henry M Kronenberg Tg(Col2a1-PTHR1H223R)AHju, transgene insertion A, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Skeletal images of wild-type and Tg(Col2a1-PTHR1H223R)BHju/Tg(Col2a1-PTHR1H223R)BHju mice (details) Represented Alleles: Tg(Col2a1-PTHR1H223R)BHju, transgene insertion B, Harald Juppner Copyright:* This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639
	Caption: Subgross analysis of skeletons of Tg(Col2a1-PTHLH)1Ecw/0 mice (details) Represented Alleles: Tg(Col2a1-PTHLH)1Ecw, transgene insertion 1, Eleanor C Weir Copyright: This image is from Weir EC, Proc Natl Acad Sci U S A 1996 Sep 17;93(19):10240-5. Copyright 1996 National Academy of Sciences, U.S.A. J:76983

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 01/20/2015 MGI 5.21