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Phenotype Images associated with this Gene
Symbol
Name
ID
Notch1
notch 1
MGI:97363


11 phenotype image(s) for Notch1 alleles
Showing image(s) 1 to 10
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Caption: Corneal plaques and increased angiogenesis in the ear of Notch1tm2Rko/Notch1tm3(cre)Rko mice (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm3(cre)Rko, notch 1; targeted mutation 3, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Notch1tm2Rko/Notch1tm3(cre)Rko mice develop vascular tumors (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm3(cre)Rko, notch 1; targeted mutation 3, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Tumor progression in Notch1tm2Rko/Notch1tm3(cre)Rko mice (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm3(cre)Rko, notch 1; targeted mutation 3, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Embryonic lethality in Notch1tm2Rko/Notch1tm4(cre)Rko embryos due to the failure of angiogenic remodeling (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm4(cre)Rko, notch 1; targeted mutation 4, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Notch1tm2Rko/Notch1tm3(cre)Rko mice show reactive splenomegaly to the inflammation in the liver (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm3(cre)Rko, notch 1; targeted mutation 3, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Liver abnormalities and inflammation in Notch1tm2Rko/Notch1tm3(cre)Rko mice (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm3(cre)Rko, notch 1; targeted mutation 3, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Well-differentiated hemangiosarcoma in Notch1tm2Rko/Notch1tm3(cre)Rko liver (details)
Represented Alleles:
Notch1tm2Rko, notch 1; targeted mutation 2, Raphael Kopan
Notch1tm3(cre)Rko, notch 1; targeted mutation 3, Raphael Kopan
Copyright: This image is from Liu Z, J Clin Invest 2011 Feb 1;121(2):800-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171829
Caption: Thin neural tube in E9.5-10.5 Notch1sot/Notch1sot embryos (details)
Represented Alleles:
Notch1sot, notch 1; sottile tubo
Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
Caption: Neural crest cell formation and migration abnormalities in Notch1sot/Notch1sot embryos (details)
Represented Alleles:
Notch1sot, notch 1; sottile tubo
Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
Caption: Agenesis or hypoplasia of neuronal differentiation in the midbrain and cranial ganglia of Notch1sot/Notch1sot embryos (details)
Represented Alleles:
Notch1sot, notch 1; sottile tubo
Copyright: This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory