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Phenotype Images associated with this Gene
Symbol
Name
ID
App
amyloid beta (A4) precursor protein
MGI:88059


4 phenotype image(s) for App alleles
Showing image(s) 1 to 4

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Click on allele symbol for full phenotype details.

Caption: Increase in creatine deposits in hippocampus of Tg(PRNP-APPSweInd)8Dwst/0 mice with age (details)
Represented Alleles:
Tg(PRNP-APPSweInd)8Dwst, transgene insertion 8, David Westaway
Copyright: This image is from Kuzyk A, J Biol Chem 2010 Oct 8;285(41):31202-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166801
Caption: Amyloid beta deposits in Tg(PRNP-APPSweInd)8Dwst/0 mouse brain (details)
Represented Alleles:
Tg(PRNP-APPSweInd)8Dwst, transgene insertion 8, David Westaway
Copyright: This image is from Kuzyk A, J Biol Chem 2010 Oct 8;285(41):31202-7 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166801
Caption: Amyloid beta deposits in Apptm3.1Zhe/Apptm3.1Zhe Psen1tm1Mpm/Psen1tm1Mpm mice (details)
Represented Alleles:
Apptm3.1Zhe, amyloid beta (A4) precursor protein; targeted mutation 3.1, Hui Zheng
Psen1tm1Mpm, presenilin 1; targeted mutation 1, Mark P Mattson
Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379
Caption: Neuromuscular synapse defects in Apptm3.1Zhe/Apptm3.1Zhe Aplp2tm1Dbo/Aplp2tm1Dbo mice (details)
Represented Alleles:
Aplp2tm1Dbo, amyloid beta (A4) precursor-like protein 2; targeted mutation 1, David R Borchelt
Apptm3.1Zhe, amyloid beta (A4) precursor protein; targeted mutation 3.1, Hui Zheng
Copyright: This image is from Li H, J Biol Chem 2010 Oct 1;285(40):30598-605 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:166379

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory