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Phenotype Images associated with this Gene
Symbol
Name
ID
Dock1
dedicator of cytokinesis 1
MGI:2429765


14 phenotype image(s) for Dock1 alleles
Showing image(s) 1 to 10
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Click on allele symbol for full phenotype details.

Caption: Mutant (E17.5) exhibits malaligned outflow tracts with hypoplastic pulmonary artery (PA) which was diagnosed by ECM histopathology as double outlet right ventricle (DORV) of Tetralogoy of Fallot subtype. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D ECM image stack in the coronal plane of mutant (E17.5) reveals double outlet right ventricle (DORV) of the Tetralogy of Fallot subtype with pulmonary atresia and subaortic VSD.
Click thumbnail to play movie. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E17.5) has severe hydrops, short snout, and micrognathia. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (e17.5) has a hypoplastic thymus (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E17.5) exhibits bilateral kidney hydronephrosis. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) exhibits abnormal outflow tracts which is diagnosed as persistent truncus arterioles (PTA, Type 1) by ECM imaging. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: EFIC Summary (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Serial 2D ECM image stack in the coronal plane of mutant (E14.5) reveals persistent truncus arteriosus (PTA-type 1), atrioventricular septal defect (AVSD), and left patent ductus arteriosis (PDA).
Click thumbnail to play movie. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213
Caption: Mutant (E14.5) exhibits hydrops, petechiae, and micrognathia. (details)
Represented Alleles:
Dock1b2b3190Clo, dedicator of cytokinesis 1; Bench to Bassinet Program (B2B/CVDC), mutation 3190Cecilia Lo
Copyright: This image is from the Laboratory of Dr. Cecilia Lo, a member of the Cardiovascular Development Consortium (CvDC), Bench to Bassinet (B2B) program of the National Heart Lung and Blood Institute (NHLBI), and is displayed with the permission of the authors. J:175213

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory