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Phenotype Images associated with this Gene
Symbol
Name
ID
Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
MGI:1891259


2 phenotype image(s) for Lrat alleles
Showing image(s) 1 to 2

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Click on allele symbol for full phenotype details.

Caption: Severe retinal degeneration in Rhotm2.1Kpal/Rhotm2.1Kpal Gnat1tm1Clma/Gnat1tm1Clma mice and less severe degeneration in Rhotm2.1Kpal/Rhotm2.1Kpal Lrattm1Kpal/Lrattm1Kpal mice (details)
Represented Alleles:
Gnat1tm1Clma, guanine nucleotide binding protein, alpha transducing 1; targeted mutation 1, C L Makino
Lrattm1Kpal, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); targeted mutation 1, Krzysztof Palczewski
Rhotm2.1Kpal, rhodopsin; targeted mutation 2.1, Krzysztof Palczewski
Copyright: This image is from Zhang N, J Clin Invest 2013 Jan 2;123(1):121-37 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194158
Caption: Effect of genetic depletion of 11-cis-retinal production (Lrattm1Kpal/Lrattm1Kpal) on retinal degeneration in Rhotm1.1Kpal/Rho+ mice (details)
Represented Alleles:
Lrattm1Kpal, lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); targeted mutation 1, Krzysztof Palczewski
Rhotm1.1Kpal, rhodopsin; targeted mutation 1.1, Krzysztof Palczewski
Rpe65450L, retinal pigment epithelium 65; 450 Leucine
Rpe65450M, retinal pigment epithelium 65; 450 Methionine
Copyright: This image is from Sakami S, J Biol Chem 2011 Mar 25;286(12):10551-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:170648

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory