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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mirc5tm1Jae
Name: microRNA cluster 5, including Mir290a through Mir295; targeted mutation 1, Rudolf Jaenisch
MGI ID: MGI:5285428
Synonyms: mir-290-295-, xmiR290 cluster -
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Some Mirc5tm1Jae/Mirc5tm1Jae embryos are observed outside the yolk sacMirc5tm1Jae/Mirc5tm1Jaeinvolves: 129S4/SvJae * C57BL/6
Reduction of germ cells in testes and ovary atrophy in Mirc5tm1Jae/Mirc5tm1Jae miceMirc5tm1Jae/Mirc5tm1Jaeinvolves: 129S4/SvJae * C57BL/6
Reduction of germ cell numbers in male and female Mirc5tm1Jae/Mirc5tm1Jae embryos as early as E11.5Mirc5tm1Jae/Mirc5tm1Jaeinvolves: 129S4/SvJae * C57BL/6
Primordial germ cells are mislocalized in Mirc5tm1Jae/Mirc5tm1Jae embryosMirc5tm1Jae/Mirc5tm1Jaeinvolves: 129S4/SvJae * C57BL/6
Male and female early postnatal gonads show germ cell depletion in Mirc5tm1Jae/Mirc5tm1Jae miceMirc5tm1Jae/Mirc5tm1Jaeinvolves: 129S4/SvJae * C57BL/6
Mirc5tm1Jae/Mirc5tm1Jae primordial germ cells are delayed in entering the hindgutMirc5tm1Jae/Mirc5tm1Jaeinvolves: 129S4/SvJae * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory