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Phenotype Images associated with this Allele
Nomenclature
Symbol: Ghrtm1.1Dlr
Name: growth hormone receptor; targeted mutation 1.1, Derek LeRoith
MGI ID: MGI:5056123
Synonyms: Ghr-floxed, GhrL
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
High fat diet-induced obesity causes impaired glucose tolerance and insulin secretion in Ghrtm1.1Dlr/Ghrtm1.1Dlr Tg(Ins2-cre)25Mgn/0 miceGhrtm1.1Dlr/Ghrtm1.1Dlr
Tg(Ins2-cre)25Mgn/0		involves: 129S4/SvJae * C3H * C57BL/6 * DBA
Reduced beta cell proliferation in obese Ghrtm1.1Dlr/Ghrtm1.1Dlr Tg(Ins2-cre)25Mgn/0 miceGhrtm1.1Dlr/Ghrtm1.1Dlr
Tg(Ins2-cre)25Mgn/0		involves: 129S4/SvJae * C3H * C57BL/6 * DBA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory