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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dclk2tm1.2Jgg
Name: doublecortin-like kinase 2; targeted mutation 1.2, Joseph G Gleeson
MGI ID: MGI:3844726
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hippocampal disorganization, increased c-fos, and loss of SOM+ interneurons in Dcxtm1Caw/Y Dclk2tm1.2Jgg/Dclk2tm1.2Jgg miceDclk2tm1.2Jgg/Dclk2tm1.2Jgg
Dcxtm1Caw/Y
involves: 129/Sv * C57BL/6
Dyslaminated interneuron populations in Dcxtm1Caw/Y Dclk2tm1.2Jgg/Dclk2tm1.2Jgg and Dcxtm1Caw/Y miceDclk2tm1.2Jgg/Dclk2tm1.2Jgg
Dcxtm1Caw/Y
involves: 129/Sv * C57BL/6
Dcxtm1Caw/Yinvolves: 129/Sv * C57BL/6
Morphological defect of Dcxtm1Caw/Y Dclk2tm1.2Jgg/Dclk2tm1.2Jgg hippocampal pyramidal cells in vivo and in vitroDclk2tm1.2Jgg/Dclk2tm1.2Jgg
Dcxtm1Caw/Y
involves: 129/Sv * C57BL/6
The Dcxtm1Caw/Y Dclk2tm1.2Jgg/Dclk2tm1.2Jgg CaBP+ interneurons within the CA field fail to relocate at the limit between the strata radiata and lacunosum molecular at P18Dclk2tm1.2Jgg/Dclk2tm1.2Jgg
Dcxtm1Caw/Y
involves: 129/Sv * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory