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Phenotype Images associated with this Allele
Nomenclature
Symbol: Il4ratm2Tch
Name: interleukin 4 receptor, alpha; targeted mutation 2, Talal A Chatila
MGI ID: MGI:3720593
Synonyms: IL-4RalphaR576, Il4raR576, Q576R
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lung histology staining of OVA-sensitized control (Q576) and Il4ratm2Tch/Il4ratm2Tch (R576) mice challenged intranasally with OVA on three consecutive daysIl4ratm2Tch/Il4ratm2TchC.129X1-Il4ratm2Tch
Increased airway inflammation and remodeling in Il4ratm2Tch/Il4ratm2Tch (R576) mice after chronic allergen challengeIl4ratm2Tch/Il4ratm2TchC.129X1-Il4ratm2Tch
Increased airway inflammation and remodeling in Il4ratm2Tch/Il4ratm2Tch (R576) mice after chronic allergen challengeIl4ratm2Tch/Il4ratm2TchC.129X1-Il4ratm2Tch
Increase in airway hyperreactivity, airway eosinophilia, and goblet cell metaplasia in Il4ratm2Tch/Il4ratm2Tch mice after IL-13 administrationIl4ratm2Tch/Il4ratm2TchC.129X1-Il4ratm2Tch

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory