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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Pdx1-cre)89.1Dam
Name: transgene insertion 89.1, Douglas A Melton
MGI ID: MGI:2684317
Synonyms: Pdx15.5-Cre, Pdx1Cre, Pdx1-Cre, Pdx1-Creearly, Pdx1-Cretg, Pdx1Tg-Cre, PDX-cre, pPdx1-Cre, Tg(Ipf1-cre)89.1Dam
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Pancreatic tumors in Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 and Krastm4Tyj/Krastm4Tyj Cdkn2atm4Rdp/Cdkn2atm4Rdp Tg(Pdx1-cre)89.1Dam/0 miceKrastm4Tyj/Krastm4Tyj
Trim33tm1Los/Trim33tm1Los
Tg(Pdx1-cre)89.1Dam/0		involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * DBA/2
Cdkn2atm4Rdp/Cdkn2atm4Rdp
Krastm4Tyj/Krastm4Tyj
Tg(Pdx1-cre)89.1Dam/0		involves: 129S4/SvJae * C57BL/6 * DBA/2
Accelerated pancreatic neoplasia in Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 mice compared to Krastm4Tyj/Krastm4Tyj Tg(Pdx1-cre)89.1Dam/0 miceKrastm4Tyj/Krastm4Tyj
Trim33tm1Los/Trim33tm1Los
Tg(Pdx1-cre)89.1Dam/0		involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * DBA/2
Krastm4Tyj/Krastm4Tyj
Tg(Pdx1-cre)89.1Dam/0		involves: 129S4/SvJae * C57BL/6 * DBA/2
Endocrine and exocrine compartments destruction in the pancreas of Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 miceKrastm4Tyj/Krastm4Tyj
Trim33tm1Los/Trim33tm1Los
Tg(Pdx1-cre)89.1Dam/0		involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * DBA/2
Presence of inflammatory cells in the pancreas associated with the cystic structures of Krastm4Tyj/Krastm4Tyj Trim33tm1Los/Trim33tm1Los Tg(Pdx1-cre)89.1Dam/0 miceKrastm4Tyj/Krastm4Tyj
Trim33tm1Los/Trim33tm1Los
Tg(Pdx1-cre)89.1Dam/0		involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 * DBA/2
Vhltm1Lss/Vhltm1Lss Tg(Pdx1-cre)89.1Dam/0 mice develop microcystic adenomas in the pancreasVhltm1Lss/Vhltm1Lss
Tg(Pdx1-cre)89.1Dam/0		involves: 129X1/SvJ * C57BL/6 * CBA
Abnormally shaped and hyperplastic islets in Vhltm1Lss/Vhltm1Lss Tg(Pdx1-cre)89.1Dam/0 miceVhltm1Lss/Vhltm1Lss
Tg(Pdx1-cre)89.1Dam/0		involves: 129X1/SvJ * C57BL/6 * CBA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory