Phenotype Images associated with this Allele - MGI

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Phenotype Images associated with this Allele

Nomenclature

Symbol:	Dcx^tm1Caw
Name:	doublecortin; targeted mutation 1, Christopher A Walsh
MGI ID:	MGI:2387757
Synonyms:	Dcx^-

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Hippocampal disorganization, increased c-fos, and loss of SOM+ interneurons in Dcx^tm1Caw/Y Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg mice	Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg Dcx^tm1Caw/Y	involves: 129/Sv * C57BL/6
	Dyslaminated interneuron populations in Dcx^tm1Caw/Y Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg and Dcx^tm1Caw/Y mice	Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg Dcx^tm1Caw/Y	involves: 129/Sv * C57BL/6
		Dcx^tm1Caw/Y	involves: 129/Sv * C57BL/6
	Morphological defect of Dcx^tm1Caw/Y Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg hippocampal pyramidal cells in vivo and in vitro	Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg Dcx^tm1Caw/Y	involves: 129/Sv * C57BL/6
	The Dcx^tm1Caw/Y Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg CaBP+ interneurons within the CA field fail to relocate at the limit between the strata radiata and lacunosum molecular at P18	Dclk2^tm1.2Jgg/Dclk2^tm1.2Jgg Dcx^tm1Caw/Y	involves: 129/Sv * C57BL/6

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