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Phenotype Images associated with this Transgene
Nomenclature
Symbol: Tg(Cd4-cre)1Cwi
Name: transgene insertion 1, Christopher B Wilson
MGI ID: MGI:2386448
Synonyms: CD4cre, CD4Cre, CD4-Cre, CD4-Cre+, CD4CRE, CD4-creTg, CD4p-Cre, Tg(CD4-cre)1Cw1
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reduced tumor growth in Fostm7Wag/Fostm7Wag Tg(Cd4-cre)1Cwi/0 mice following carcinoma cell inoculationFostm7Wag/Fostm7Wag
Tg(Cd4-cre)1Cwi/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Reduced tumor growth in Fostm7Wag/Fostm7Wag Tg(Cd4-cre)1Cwi/0 mice following carcinoma cell inoculationFostm7Wag/Fostm7Wag
Tg(Cd4-cre)1Cwi/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Enlarged spleen in Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+ Tg(Cd4-cre)1Cwi/0 miceGt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Disruption of the splenic architecture with highly proliferative cells and solid organ infiltration of abnromal CD3+ T cells in Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+ Tg(Cd4-cre)1Cwi/0 miceGt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+
Tg(Cd4-cre)1Cwi/0		involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Plcg1tm1Rwen/Plcg1tm1Gcrp Tg(Cd4-cre)1Cwi/0 mice develop inflammatory/autoimmune diseasePlcg1tm1Gcrp/Plcg1tm1Rwen
Tg(Cd4-cre)1Cwi/0		either: B6.Cg-Plcg1tm1Gcrp/Plcg1tm1Rwen Tg(Cd4-cre)1Cwi or (involves: 129X1/SvJ * C57BL/6 * DBA/2)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory