About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Myl2tm1(cre)Krc
Name: myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien
MGI ID: MGI:2385922
Synonyms: MLC-2v -, Mlc2v-cre, MLC2v-cre, MLC2vcreKI
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Autophagosome accumulation in Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ heartsMfn2tm1.1Mzhe/Mfn2tm1.1Mzhe
Myl2tm1(cre)Krc/Myl2+		involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J
Impaired lipid metabolism and accumulation of lipofuscin granules in Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ cardiomyocytesMfn2tm1.1Mzhe/Mfn2tm1.1Mzhe
Myl2tm1(cre)Krc/Myl2+		involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J
Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ cardiomyocytes show a greater loss of mitochondrial membrane potential following ischemia-reperfusionMfn2tm1.1Mzhe/Mfn2tm1.1Mzhe
Myl2tm1(cre)Krc/Myl2+		involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J
Enlarged mitochondria in Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ heartMfn2tm1.1Mzhe/Mfn2tm1.1Mzhe
Myl2tm1(cre)Krc/Myl2+		involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory