About   Help   FAQ
Phenotype Images associated with this Allele
Nomenclature
Symbol: Upk3atm1Tsun
Name: uroplakin 3A; targeted mutation 1, Tung-Tien Sun
MGI ID: MGI:2183244
Synonyms: UPIII(-)
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Upk2tm1Tsun/Upk2tm1Tsun mice exhibit ureteral obstructionUpk2tm1Tsun/Upk2tm1Tsuninvolves: 129S/SvEv * Black Swiss
Urothelium lacks the umbrella cells and is leaky in Upk3atm1Tsun/Upk3atm1Tsun miceUpk3atm1Tsun/Upk3atm1Tsuneither: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
Upk3atm1Tsun/Upk3atm1Tsun mice have an altered urothelial apical surface and enlarged ureteral orificeUpk3atm1Tsun/Upk3atm1Tsuneither: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
Upk3atm1Tsun/Upk3atm1Tsun urothelium lacks uroplakin-containing fusiform vesicles and normal, apical urothelial plaquesUpk3atm1Tsun/Upk3atm1Tsuneither: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
Upk3atm1Tsun/Upk3atm1Tsun mice develop hydronephrosis and kidney abnormalitiesUpk3atm1Tsun/Upk3atm1Tsuneither: (involves: 129S/SvEv) or (involves: 129S/SvEv * Swiss Webster)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory