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Phenotype Images associated with this Allele
Nomenclature
Symbol: Spp1tm1Blh
Name: secreted phosphoprotein 1; targeted mutation 1, Brigid L Hogan
MGI ID: MGI:1932083
Synonyms: eta1, Eta-1, Opn-, OPN-, OPN-KO
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Reduction in neutrophils in Dmdmdx/Y Spp1tm1Blh/Spp1tm1Blh and Dmdmdx/Dmdmdx Spp1tm1Blh/Spp1tm1Blh muscles compared to Dmdmdx/Dmdmdx musclesDmdmdx/Y
Spp1tm1Blh/Spp1tm1Blh
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
Dmdmdx/Dmdmdx
Spp1tm1Blh/Spp1tm1Blh
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
Reduced diaphragm and cardiac fibrosis in Dmdmdx/Y Spp1tm1Blh/Spp1tm1Blh and Dmdmdx/Dmdmdx Spp1tm1Blh/Spp1tm1Blh mice compared to Dmdmdx/Dmdmdx miceDmdmdx/Y
Spp1tm1Blh/Spp1tm1Blh
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn
Dmdmdx/Dmdmdx
Spp1tm1Blh/Spp1tm1Blh
involves: 129S6/SvEvTac * C57BL/6 * C57BL/10 * C57BL/10ScSn

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory