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Phenotype Image Detail
Image
Caption General and heart phenotype of Hspb7tm1.1Chen/Hspb7tm1.1Chen Nkx2-5tm1(cre)Rjs/Nkx2-5+ mice. (C) Hematoxylin and eosin (H&E) images of E11.5 control and Hspb7tm1.1Chen/Hspb7tm1.1Chen Nkx2-5tm1(cre)Rjs/Nkx2-5+ (cKO (Nkx2.5-Cre)) embryos acquired using NanoZoomer slide scanner. (Scale bar: 0.5 mm.) Estimated location of sectioning is indicated by a dotted line on the whole-mount embryos images to the left. (Scale bar: 1 mm.) Magnified right ventricle (RV; red box) and left ventricle (LV; green box) wall views are shown to the right. Left and right ventricle wall thicknesses are indicated by rulers. (Scale bar: 0.1 mm.)
Copyright This image is from Wu T, Proc Natl Acad Sci U S A 2017 Nov 7;114(45):11956-11961. Copyright 2017 National Academy of Sciences, U.S.A. J:256653
Associated
Alleles
Symbol Name
Hspb7tm1.1Chen heat shock protein family, member 7 (cardiovascular); targeted mutation 1.1, Ju Chen
Nkx2-5tm1(cre)Rjs NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Associated
Genotypes
Allelic Composition Genetic Background
Hspb7tm1.1Chen/Hspb7tm1.1Chen
Nkx2-5tm1(cre)Rjs/Nkx2-5+ 		involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory