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Phenotype Image Detail
Image
Caption (B) Representative spleens from 50-week-old control and Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+ Cd19tm1(cre)Cgn/Cd19+ (ITK-SYKCD19-Cre) mice are shown (in centimeters). (C) Solid organ infiltration with abnormally proliferating T cells in the mutant mice. H&E staining and immunohistochemistry with anti-CD3 and anti-Ki-67 antibodies wereperformed on liver (LIV) and lung (LNG) sections. Bars, 1 mm. Data representative of six diseased mutant mice are shown.
Copyright This image is from Pechloff K, J Exp Med 2010 May 10;207(5):1031-44, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:160931
Associated
Alleles
Symbol Name
Gt(ROSA)26Sortm1(ITK/SYK)Jrld gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jurgen Ruland
Associated
Genotypes
Allelic Composition Genetic Background
Cd19tm1(cre)Cgn/Cd19+
Gt(ROSA)26Sortm1(ITK/SYK)Jrld/Gt(ROSA)26Sor+
involves: 129P2/OlaHsd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory