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Phenotype Image Detail
Image
Caption Genetic interaction between Bmp4 and Bmp7 during the caudal body formation. (C-D) Whole-mount view and (G-H) mid-sagittal sections of wild-type (WT) and Bmp4tm4Blh/Bmp4+ Bmp7tm1.1Dgra/Bmp7tm1.1Dgra Hoxa3tm1(cre)Moon/Hoxa3+ (mutant) embryos. Red arrowheads indicate the hindlimb position. (D). The compound mutant mice show bladder aplasia (H) and anal stenosis (arrow in H). dGT, dorsal GT; b, bladder; r, rectum.
Copyright This image is from Suzuki K, PLoS One 2012;7(9):e43453, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:192045
Associated
Alleles
Symbol Name
Bmp4tm4Blh bone morphogenetic protein 4; targeted mutation 4, Brigid L Hogan
Bmp7tm1.1Dgra bone morphogenetic protein 7; targeted mutation 1.1, Daniel Graf
Hoxa3tm1(cre)Moon homeobox A3; targeted mutation 1, Anne M Moon
Associated
Genotypes
Allelic Composition Genetic Background
Bmp4tm4Blh/Bmp4+
Bmp7tm1.1Dgra/Bmp7tm1.1Dgra
Hoxa3tm1(cre)Moon/Hoxa3+
involves: 129S6/SvEvTac * C57BL/6NTac

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory