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Phenotype Image Detail
Image
Caption Deleting Ctsk in hematopoietic cells and osteoclasts increases cancellous bone mass. uCT and x-ray images of femurs from controls (Ctrl) and Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Mx1-cre)1Cgn/0 (cKO Mx1) and Ctsktm1.1Rbar/Ctsktm1.1Rbar Tg(Itgam-cre)AJva/0 (cKO CD11b) mice at 9 weeks of age.
Copyright This image is from Lotinun S, J Clin Invest 2013 Jan 16;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194492
Associated
Alleles
Symbol Name
Ctsktm1.1Rbar cathepsin K; targeted mutation 1.1, Roland Baron
Tg(Itgam-cre)AJva transgene insertion A, Jean Vacher
Tg(Mx1-cre)1Cgn transgene insertion 1, University of Cologne
Associated
Genotypes
Allelic Composition Genetic Background
Ctsktm1.1Rbar/Ctsktm1.1Rbar
Tg(Itgam-cre)AJva/0 		involves: C57BL/6
Ctsktm1.1Rbar/Ctsktm1.1Rbar
Tg(Mx1-cre)1Cgn/0 		involves: C57BL/6 * CBA
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory