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Phenotype Image Detail
Image
Caption Representative sections of Peyer's patches from wild-type (SPPL2a+/+) and Sppl2atm1Basc/Sppl2atm1Basc (SPPL2a-/-) mice were stained with hematoxylin and eosin or used for immunohistochemical visualization of B220+ B cells. The B cell deficiency is reflected in atrophic Peyer's patches. Bars, 500 um.
Copyright This image is from Schneppenheim J, J Exp Med 2013 Jan 14;210(1):41-58, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:194664
Associated
Alleles
Symbol Name
Sppl2atm1Basc signal peptide peptidase like 2A; targeted mutation 1, Bernd Schroder
Associated
Genotypes
Allelic Composition Genetic Background
Sppl2atm1Basc/Sppl2atm1Basc involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory