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Phenotype Image Detail
Image
Caption B, Morphological features of tumors derived from 14-week old female Tg(MMTV-PyVT)634Mul/0 [PyVT(+/-)/ADN(+/+)] and Tg(MMTV-PyVT)634Mul/0 Adipoqtm1Chan/Adipoq+ [PyVT(+/-)/ADN(+/-)] mice of the FVB/N background. Distinct morphologies were observed between tumors collected from mice with normal and reduced adiponectin levels. Note that central necrosis and geographic tumor necrosis, as well as stromal lymphocytic responses represented the typical basal-like subtype of breast tumors in PyVT(+/-)/ADN(+/-) mice.
Copyright This image is from Lam JB, PLoS ONE 2009;4(3):e4968, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:147458
Associated
Alleles
Symbol Name
Adipoqtm1Chan adiponectin, C1Q and collagen domain containing; targeted mutation 1, Lawrence Chan
Tg(MMTV-PyVT)634Mul transgene insertion 634, William Muller
Associated
Genotypes
Allelic Composition Genetic Background
Adipoqtm1Chan/Adipoq+
Tg(MMTV-PyVT)634Mul/0
FVB.Cg-Adipoqtm1Chan Tg(MMTV-PyVT)634Mul

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory