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Phenotype Image Detail
Image
Caption A: A slit lamp photo shows the dominant lamellar cataract of a CrygbClapper/Crygb+ (I4F/+) mouse at adulthood (indicated by arrows). B: A set of fresh lenses from wild type (+/+), heterozygous, and CrygbClapper/CrygbClapper (I4F/I4F) littermates at 3 weeks old. Scale bar, 1mm. Photos show retinal fundus (C1-C3), angiography (D1-D3), and the lenses (E1-E3) of a 30 day old wild type (C1, D1 and E1), a 21 day old homozygous mouse (C2,D2 and E2), a 3 month old homozygous mouse for the lens and fundus images (C3 and E3), and a 6 month old homozygous mouse for the angiography (D3). White arrowheads indicate retinal vessels. Scale bar, 1mm for lenses.
Copyright This image is from Liu H, J Biol Chem 2005 Jul 1;280(26):25071-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:100851
Associated
Alleles
Symbol Name
CrygbClapper crystallin, gamma B; Clapper
Associated
Genotypes
Allelic Composition Genetic Background
CrygbClapper/CrygbClapper C57BL/6J-CrygbClapper
CrygbClapper/Crygb+ C57BL/6J-CrygbClapper

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory