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| Caption | A comparative study of Egfrwa2/Egfrwa2 (A, C, & E) and Egfrwa2/Egfrwa2 Ptpn11tm1Paw/+ (B,D & F) newborn mice. A & B: Section of abdomenal skins. In severely affected Egfrwa2/Egfrwa2 Ptpn11tm1Paw/+ mouse, skin was poorly developed with no or few disorganized hair follicles, thinner epidermis, reduced subcutaneous fat or muscle tissue mass. Hematoxylin/eosin stained. C & D: Lung sections. There was a marked reduction in the size of aveolar spaces (atelectasis) and an increase in the thickness of aveolar walls in the Egfrwa2/Egfrwa2 Ptpn11tm1Paw/+ mice. Hematoxylin/eosin stained. E & F: Small bowel. The lumen is filled with desquamated cells, giving a solid appearance. Hematoxylin/ eosin stained. Magnifications: A,B,E & F: x280; C & D: x200 | ||||||
| Copyright | This image is from Qu CK, Proc Natl Acad Sci U S A 1999 Jul 20;96(15):8528-33. Copyright 1999 National Academy of Sciences, U.S.A. J:75413 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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