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Phenotype Image Detail
Image
Caption Radial sections in lower magnification (upper) and photoreceptors at higher magnification (lower). For both +/+ wild-type and Plcb4tm1Dwu/Plcb4tm1Dwu mice there was little variation across retinal eccentricities; average thickness for wild-type was 188 +/-8 and for the homozygous mutants 208 +/-3. In addition, retinal morphology in the homozygous mutant (right) appeared normal compared with that in the wild-type mouse. Abbreviations: pigment epithelium (PE); outer segment (OS); inner segment (IS); outer nuclear alyer (ONL); outer plexiform layer (OPL); inner nuclear layer (INL); inner plexiform layer (IPL) ganglion cell layer (GCL).
Copyright This image is from Jiang H, Proc Natl Acad Sci U S A 1996 Dec 10;93(25):14598-601. Copyright 1996 National Academy of Sciences, U.S.A. J:77638
Associated
Alleles
Symbol Name
Plcb4tm1Dwu phospholipase C, beta 4; targeted mutation 1, Dianqing Wu
Associated
Genotypes
Allelic Composition Genetic Background
Plcb4tm1Dwu/Plcb4tm1Dwu involves: 129S1/Sv

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory