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Molecular Image Detail
Image
Caption Targeting of the mouse Lyl1 genomic locus. (a) Schematic representation of the Lyl1 genomic locus. Map and restriction enzyme sites demonstrate the strategy used for targeting and screening ES clones. Thick lines indicate the DNA sequence used for homologous recombination, the black arrow indicates the PGK promoter that drives the neomycin resistance gene, and the grey arrows indicate the loxP sites. The diphtheria toxin gene (DTA) was used for negative selection. BamHI and BglI sites were used for screening the 3' and 5' regions, respectively.
Copyright This image is from Souroullas GP, Genesis 2011 Jun;49(6):441-8, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:173665
Associated
Alleles
Symbol Name
Lyl1tm1Mago lymphoblastomic leukemia 1; targeted mutation 1, Margaret A Goodell

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory