Lyl1^tm1Mago
Targeted Allele Detail

Summary

• Symbol: Lyl1^tm1Mago
• Name: lymphoblastomic leukemia 1; targeted mutation 1, Margaret A Goodell
• MGI ID: MGI:5050110
• Synonyms: Lyl1^Mg
• Gene: Lyl1 Location: Chr8:85428078-85431569 bp, + strand Genetic Position: Chr8, 41.02 cM
• Alliance: Lyl1^tm1Mago page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:173665
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exons 1-4 were replaced with a floxed PGK-neomycin selection cassette. The selection cassette was not removed. (J:173665)

Generation of the Lyl1^tm1Mago allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lyl1 Mutation: 9 strains or lines available

References

• Original: J:173665 Souroullas GP, et al., A new allele of Lyl1 confirms its important role in hematopoietic stem cell function. Genesis. 2011 Jun;49(6):441-8
• All: 3 reference(s)