Phenotype Image Detail

Image

Caption

Heart morphologies of control and Acvrl1^tm2.1Spo/Acvrl1^tm2.1Spo Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺ mice 8 days after tamoxifen treatment show enlarged heart in the mutants. Scale bar indicates 3 mm. B. Heart/body weight ratio is significantly increased in the mutant. * p < 0.0001.

Copyright

This image is from Park SO, J Clin Invest 2009 Nov;119(11):3487-96 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:154620

Associated Alleles

Symbol	Name
Acvrl1^tm2.1Spo	activin A receptor, type II-like 1; targeted mutation 2.1, S Paul Oh
Gt(ROSA)26Sor^tm1(cre/ERT)Nat	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jeremy Nathans

Associated Genotypes

Allelic Composition	Genetic Background
Acvrl1^tm2.1Spo/Acvrl1^tm2.1Spo Gt(ROSA)26Sor^tm1(cre/ERT)Nat/Gt(ROSA)26Sor^+	involves: 129 * 129S1/Sv * 129X1/SvJ