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| Caption | Bright and fluorescent images of PECAM-1 immunostained E9.5-10.5 (a) wild-type and (b) Kdrorv/Kdrorv (orvieto) embryos. Arrowheads and arrows indicate perturbed pharyngeal arch artery formation and anomalies in vascular plexus development, respectively. Mutant embryos are devoid of any vasculature. PECAM-1 staining reveals the total absence of endothelial cells, primary vessels and secondary capillaries along with failure of chorio-allantoic fusion. | ||||
| Copyright | This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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