Phenotype Image Detail

Image

Caption

(B). Representative sections of the cecum showed increased levels of active caspase-3 in H. histolytica-infected Lepr^tm1.1Rll/Lepr^tm1.1Rll (R/R) mice. Original magnification, 100. (C) Higher magnification demonstrated undetectable active caspase-3 staining in wild-type (Q/Q) intestinal epithelial cells (IECs) (left), but cytoplasmic and perinuclear staining in R/R IECs (middle, arrows) and infiltrating cells (right). Original magnification, 400.

Copyright

This image is from Duggal P, J Clin Invest 2011 Mar 1;121(3):1191-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172012

Associated Alleles

Symbol	Name
Lepr^tm1.1Rll	leptin receptor; targeted mutation 1.1, Rudolph L Leibel

Associated Genotypes

Allelic Composition	Genetic Background
Lepr^tm1.1Rll/Lepr^tm1.1Rll	129P3/J-Lepr^tm1.1Rll