Phenotype Image Detail

Image

Caption

Phenotypic analysis of Itm2a mutant embryos. F-H, X-Gal staining of Itm2a^tm1.1Buck/Y (Itm2a^XcdKO/Y) (F), Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3⁺ (Pax3^Cre/+ Itm2a^XcdKO/Y) (G) and Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3^tm1(cre)Joe (Itm2a^XcdKO/Y Pax3^Cre/Cre) (H) embryos at E9.5. I-J, X-Gal staining of Itm2a^tm1.2Buck/Y (Itm2a^XKO/Y) (I), Itm2a^tm1.2Buck/Y Pax3^tm4Buck/Pax3⁺ (Pax3^GFP/+ Itm2a^XKO/Y) (J) and Itm2a^tm1.2Buck/Y Pax3^tm4Buck/Pax3^tm4Buck (Pax3^GFP/GFPItm2a^XKO/Y) (K) embryos at E11.5.

Copyright

This image is from Lagha M, PLoS One 2013;8(5):e63143, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200546

Associated Alleles

Symbol	Name
Itm2a^tm1.1Buck	integral membrane protein 2A; targeted mutation 1.1, Margaret E Buckingham
Itm2a^tm1.2Buck	integral membrane protein 2A; targeted mutation 1.2, Margaret E Buckingham
Pax3^tm1(cre)Joe	paired box 3; targeted mutation 1, Jonathan A Epstein
Pax3^tm4Buck	paired box 3; targeted mutation 4, Margaret Buckingham

Associated Genotypes

Allelic Composition	Genetic Background
Itm2a^tm1.1Buck/Y	involves: C57BL/6
Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3^+	involves: C57BL/6
Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3^tm1(cre)Joe	involves: C57BL/6
Itm2a^tm1.2Buck/Y Pax3^tm4Buck/Pax3^tm4Buck	involves: C57BL/6