Phenotype Image Detail

Image

Caption

Phenotype of Chrd^tm1Emdr/Chrd^tm1Emdr (Chrd-/-) embryos. (A-G) Comparison of organ structures in wild-type and mutant embryos at embryonic day (E) 15.5. Ears of mutant embryos are abnormally located and fail to form auricle structures (A, B). Athymia, persistent truncus arteriosus (PTA; failure of outflow tract septation) and abnormal aortic arch artery structure are observed in the mutant (C-E). Cleft palate (CP) is also a feature of the mutant embryos (F, G).

Copyright

This image is from Choi M, PLoS Genet 2009 Feb;5(2):e1000395, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:146769

Associated Alleles

Symbol	Name
Chrd^tm1Emdr	chordin; targeted mutation 1, EM De Robertis

Associated Genotypes

Allelic Composition	Genetic Background
Chrd^tm1Emdr/Chrd^tm1Emdr	129S6.129-Chrd^tm1Emdr