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Phenotype Image Detail
Image
Caption A: Periodic acid Schiff's staining of postischemic kidneys. Shown are stainings for wild type (WT, Upper Left), Bdkrb2tm1Jfh/Bdkrb2tm1Jfh (B2R-null, Upper Right), and Bdkrb2/Bdkrb1tm1Mki/Bdkrb2/Bdkrb1tm1Mki (B1RB2R-null, Lower) mice. Scale bar, 100um. B: Semiquantitative scoring for histological changes in the proximal tubule according to the criteria of Jablonski et al. (56). The sham-operated mice all a score of zero. The black columns show the scores of the ischemia groups. P<0.05 vs WT; P<0.05 vs. B2R-null. The data are means +/- standard errors, with the numbers of mice shown in white digits.
Copyright This image is from Kakoki M, Proc Natl Acad Sci U S A 2007 May 1;104(18):7576-81. Copyright 2007 National Academy of Sciences, U.S.A. J:121339
Associated
Alleles
Symbol Name
Bdkrb2/Bdkrb1tm1Mki bradykinin receptor, beta 1; targeted mutation 1, Masao Kakoki
Bdkrb2/Bdkrb1tm1Mki bradykinin receptor, beta 2; targeted mutation 1, Masao Kakoki
Bdkrb2tm1Jfh bradykinin receptor, beta 2; targeted mutation 1, J Fred Hess
Associated
Genotypes
Allelic Composition Genetic Background
Bdkrb2tm1Jfh/Bdkrb2tm1Jfh B6.129S7-Bdkrb2tm1Jfh
Bdkrb2/Bdkrb1tm1Mki/Bdkrb2/Bdkrb1tm1Mki involves: C57BL/6J
Bdkrb2/Bdkrb1tm1Mki/Bdkrb2/Bdkrb1tm1Mki involves: C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory