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Phenotype Image Detail
Image
Caption A: E12.5 wild type mouse. B: E12.5 Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn mouse. C: E12.5 Fgf10tm1Ska/Fgf10tm1Ska mouse. In the wild type mouse (A), the Initial Bud Stage submandibular gland (SMG) is seen in the mandible ventrolateral to the tongue. By contrast, the SMG bud (outlined in white in the Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn (B) and Fgf10tm1Ska/Fgf10tm1Ska (C) mice is extremely small, resembling the earliest Initial Bud Stage SMG. Scalebar, 50um.
Copyright This image is from Jaskoll T, BMC Dev Biol 2005;5():11, an open-access article, licensee BioMed Central Ltd. J:119849
Associated
Alleles
Symbol Name
Fgf10tm1Ska fibroblast growth factor 10; targeted mutation 1, Shigeaki Kato
Fgfr2tm1.1Dsn fibroblast growth factor receptor 2; targeted mutation 1.1, Clive Dickson
Associated
Genotypes
Allelic Composition Genetic Background
Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn involves: 129P2/OlaHsd * C57BL/6
Fgf10tm1Ska/Fgf10tm1Ska involves: C57BL/6 * CBA

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory