PSAP Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	PSAP	HGNC:9498 (HGNC) 5660 (Entrez Gene) 176801 (OMIM) PSAP (Alliance of Genome Resources)	Chr10 q22.1	Chr10:71816298-71851251 (-) GRCh38	atypical Gaucher's disease due to saposin c deficiency combined saposin deficiency late onset Parkinson's disease	P07602 (UniProt \| EBI) NM_001042466 (RefSeq)
mouse	Psap	MGI:97783 (MGI) 19156 (Entrez Gene) Gene Tree Psap (Alliance of Genome Resources)	Chr10 30.02 cM	Chr10:60113449-60138376 (+) GRCm39	combined saposin deficiency Krabbe disease metachromatic leukodystrophy	ENSMUSG00000004207 (Ensembl Gene Model) ENSMUSP00000137476 (Ensembl) ENSMUST00000179238 (Ensembl)
rat	Psap	RGD:3423 (Rat Genome Database) 25524 (Entrez Gene) Psap (Alliance of Genome Resources)	Chr20 q11			P10960 (UniProt \| EBI) NM_001190238 (RefSeq)
zebrafish	psap	ZDB-GENE-020108-1 (Zebrafish Model Organism Database) 140811 (Entrez Gene) psap (Alliance of Genome Resources)	Chr13			NP_001296196 (RefSeq) NM_001309267 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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