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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MYC HGNC:7553 (HGNC)
4609 (Entrez Gene)
190080 (OMIM)
MYC (Alliance of Genome Resources)
Chr8 q24.21 Chr8:127735434-127742951 (+)
GRCh38
acute promyelocytic leukemia
angiosarcoma
breast cancer
Burkitt lymphoma
demyelinating disease
lung adenocarcinoma
prostate adenocarcinoma
prostate cancer
urinary bladder cancer
P01106 (UniProt | EBI)
NM_001354870 (RefSeq)
mouse Myc MGI:97250 (MGI)
17869 (Entrez Gene)
Gene Tree
Myc (Alliance of Genome Resources)
Chr15 26.19 cM Chr15:61857240-61862223 (+)
GRCm39
autosomal dominant polycystic kidney disease
breast cancer
Burkitt lymphoma
hepatocellular carcinoma
pancreatic carcinoma
ENSMUSG00000022346 (Ensembl Gene Model)
ENSMUSP00000022971 (Ensembl)
ENSMUST00000022971 (Ensembl)
rat Myc RGD:3130 (Rat Genome Database)
24577 (Entrez Gene)
Myc (Alliance of Genome Resources)
Chr7 q33 P09416 (UniProt | EBI)
NM_012603 (RefSeq)
zebrafish myca ZDB-GENE-990415-162 (Zebrafish Model Organism Database)
30686 (Entrez Gene)
myca (Alliance of Genome Resources)
Chr24 P52160 (UniProt | EBI)
NM_131412 (RefSeq)
mycb ZDB-GENE-040426-780 (Zebrafish Model Organism Database)
393141 (Entrez Gene)
mycb (Alliance of Genome Resources)
Chr2 Q7ZVS9 (UniProt | EBI)
NM_200172 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory