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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
37277

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LIPA HGNC:6617 (HGNC)
3988 (Entrez Gene)
613497 (OMIM)
Chr10 q23.2-q23.3 Chr10:89213569-89252039 (-)
GRCh38
Lysosomal Acid Lipase Deficiency
P38571 (UniProt | EBI)
NM_000235 (RefSeq)
mouse Lipa MGI:96789 (MGI)
16889 (Entrez Gene)
Gene Tree
VISTA-Point
Chr19 29.7 cM Chr19:34492318-34527474 (-)
GRCm38
Lysosomal Acid Lipase Deficiency
ENSMUSG00000024781 (Ensembl Gene Model)
ENSMUSP00000053270 (Ensembl)
ENSMUST00000049572 (Ensembl)
rat Lipa 25055 (Entrez Gene)
Chr1 q52 Q64194 (UniProt | EBI)
NM_012732 (RefSeq)
chimpanzee LIPA 466150 (Entrez Gene)
Chr10 XP_521552 (RefSeq)
rhesus macaque LIPA 695240 (Entrez Gene)
Chr9 NP_001253275 (RefSeq)
NM_001266346 (RefSeq)
cattle LIPA 100125267 (Entrez Gene)
Chr26 NP_001096793 (RefSeq)
NM_001103323 (RefSeq)
dog LIPA 100856363 (Entrez Gene)
Chr26 XP_003639974 (RefSeq)
chicken LIPA 423789 (Entrez Gene)
Chr6 XP_421661 (RefSeq)
western clawed frog lipa 548564 (Entrez Gene)
ChrUN NP_001015847 (RefSeq)
NM_001015847 (RefSeq)
zebrafish lipf 406713 (Entrez Gene)
Chr12 NP_998569 (RefSeq)
NM_213404 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory