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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human COL4A1 HGNC:2202 (HGNC)
1282 (Entrez Gene)
120130 (OMIM)
HGNC homology
Chr13 q34 Chr13:110148958-110307157 (-)
COL4A1-related familial vascular leukoencephalopathy
P02462 (UniProt | EBI)
NM_001845 (RefSeq)
mouse Col4a1 MGI:88454 (MGI)
12826 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 5.53 cM Chr8:11198423-11312826 (-)
COL4A1-related familial vascular leukoencephalopathy
kidney disease
Walker-Warburg syndrome
OTTMUSG00000021316 (VEGA)
OTTMUSP00000023605 (VEGA)
OTTMUST00000050536 (VEGA)
rat Col4a1 290905 (Entrez Gene)
Chr16 q12.5 NP_001128481 (RefSeq)
NM_001135009 (RefSeq)
chimpanzee COL4A1 452659 (Entrez Gene)
Chr13 XP_016781016 (RefSeq)
cattle COL4A1 282191 (Entrez Gene)
Chr12 Q7SIB2 (UniProt | EBI)
NM_001166511 (RefSeq)
dog COL4A1 403496 (Entrez Gene)
Chr22 XP_022263934 (RefSeq)
NM_001197103 (RefSeq)
chicken COL4A1 395530 (Entrez Gene)
Chr1 NP_001155871 (RefSeq)
NM_001162399 (RefSeq)
zebrafish col4a1 554269 (Entrez Gene)
Chr9 XP_694040 (RefSeq)
frog, western clawed col4a1 100124870 (Entrez Gene)
Chr2 XP_002933064 (RefSeq)
macaque, rhesus COL4A1 700281 (Entrez Gene)
Chr17 XP_014976931 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory