BRAF Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	BRAF	HGNC:1097 (HGNC) 673 (Entrez Gene) 164757 (OMIM) BRAF (Alliance of Genome Resources)	Chr7 q34	Chr7:140713328-140924929 (-) GRCh38	bile duct adenoma cardiofaciocutaneous syndrome cardiofaciocutaneous syndrome 1 cholangiocarcinoma colon carcinoma colorectal adenocarcinoma colorectal cancer dysembryoplastic neuroepithelial tumor endometrial carcinoma familial melanoma germinoma intrahepatic cholangiocarcinoma malignant astrocytoma melanoma Noonan syndrome 7 Noonan syndrome with multiple lentigines 3 pancreatic acinar cell adenocarcinoma pancreatic cancer pleomorphic xanthoastrocytoma prostate adenocarcinoma thyroid gland papillary carcinoma	P15056 (UniProt \| EBI) NM_001378475 (RefSeq)
mouse	Braf	MGI:88190 (MGI) 109880 (Entrez Gene) Gene Tree Braf (Alliance of Genome Resources)	Chr6 18.43 cM	Chr6:39580171-39702397 (-) GRCm39	cardiofaciocutaneous syndrome Langerhans-cell histiocytosis melanoma thyroid gland papillary carcinoma	ENSMUSG00000002413 (Ensembl Gene Model) ENSMUSP00000002487 (Ensembl) ENSMUST00000002487 (Ensembl)
rat	Braf	RGD:619908 (Rat Genome Database) 114486 (Entrez Gene) Braf (Alliance of Genome Resources)	Chr4 q23			NP_001414395 (RefSeq) NM_001427466 (RefSeq)
zebrafish	braf	ZDB-GENE-040805-1 (Zebrafish Model Organism Database) 403065 (Entrez Gene) braf (Alliance of Genome Resources)	Chr4			NP_991307 (RefSeq) NM_205744 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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