DPYD Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	DPYD	HGNC:3012 (HGNC) 1806 (Entrez Gene) 612779 (OMIM) DPYD (Alliance of Genome Resources)	Chr1 p21.3	Chr1:97077743-97995000 (-) GRCh38	acute lymphoblastic leukemia dihydropyrimidine dehydrogenase deficiency pancreatic cancer	Q12882 (UniProt \| EBI) NM_000110 (RefSeq)
mouse	Dpyd	MGI:2139667 (MGI) 99586 (Entrez Gene) Gene Tree Dpyd (Alliance of Genome Resources)	Chr3 51.96 cM	Chr3:118355778-119226573 (+) GRCm39		ENSMUSG00000033308 (Ensembl Gene Model) ENSMUSP00000039429 (Ensembl) ENSMUST00000039177 (Ensembl)
rat	Dpyd	RGD:621218 (Rat Genome Database) 81656 (Entrez Gene) Dpyd (Alliance of Genome Resources)	Chr2 q42			O89000 (UniProt \| EBI) NM_031027 (RefSeq)
zebrafish	dpyda.1	ZDB-GENE-061013-727 (Zebrafish Model Organism Database) 768165 (Entrez Gene) dpyda.1 (Alliance of Genome Resources)	Chr24			NP_001070776 (RefSeq) NM_001077308 (RefSeq)
zebrafish	dpydb	ZDB-GENE-040426-2459 (Zebrafish Model Organism Database) 405829 (Entrez Gene) dpydb (Alliance of Genome Resources)	Chr2			Q6NYG8 (UniProt \| EBI) NM_212893 (RefSeq)